The Ketogenic Diet

A Therapeutic Approach to Wellness

In recent years, the ketogenic diet has surged in popularity, not just as a weight loss strategy, but as a potential therapeutic tool for various health conditions. As the founder of Natural Ketosis, I’ve witnessed firsthand the transformative power of this high-fat, moderate-protein, and low-carbohydrate approach.

Let’s delve deeper into what the ketogenic diet entails, how to achieve ketosis, and its promising therapeutic applications.

Understanding the Ketogenic Diet

The ketogenic diet, often abbreviated as “keto,” is a nutritional approach that fundamentally alters the way our body uses energy. Traditionally, our bodies rely on glucose derived from carbohydrates as the primary fuel source. However, when we drastically reduce carbohydrate intake and increase fat consumption, our body enters a metabolic state called ketosis.

In ketosis, the liver begins to break down fatty acids into ketone bodies, or ketones, which serve as an alternative energy source for the brain and body. This shift from glucose to ketones as the primary fuel can lead to numerous physiological changes, many of which are associated with improved health outcomes.

The Biochemistry of Ketosis

To truly appreciate the ketogenic diet, it’s crucial to understand the biochemical processes involved. When carbohydrate intake is severely restricted (typically to less than 50 grams per day), the body’s glycogen stores become depleted. As a result, insulin levels drop, and the body starts to mobilise stored fat for energy.

The liver then converts fatty acids into ketones through a process called ketogenesis. The three main types of ketones produced are:

  1. Acetoacetate
  2. Beta-hydroxybutyrate (BHB)
  3. Acetone

These ketones can cross the blood-brain barrier, providing an efficient energy source for the brain. This is particularly significant because while most body tissues can use fatty acids directly for energy, the brain typically relies on glucose. The ability of the brain to use ketones for fuel is a key factor in many of the diet’s therapeutic applications.

Therapeutic Applications of the Ketogenic Diet

The ketogenic diet’s potential extends far beyond weight loss. Research has shown promising results in various health conditions:

  1. Epilepsy: The diet has been used since the 1920s to help control seizures, particularly in children with drug-resistant epilepsy. It’s thought that ketones may have an anti-epileptic effect, possibly by altering neurotransmitter levels or enhancing mitochondrial function.
  2. Type 2 Diabetes: By significantly reducing carbohydrate intake, the ketogenic diet can help improve insulin sensitivity and blood sugar control. Some studies have shown that it may even lead to remission of type 2 diabetes in some individuals.
  3. Neurological disorders: Emerging research suggests potential benefits for conditions like Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The neuroprotective effects of ketones and the diet’s anti-inflammatory properties may play a role in these potential benefits.
  4. Polycystic Ovary Syndrome (PCOS): The diet may help reduce insulin levels and improve insulin sensitivity, potentially leading to better hormone balance and improved fertility in women with PCOS.
  5. Cardiovascular health: Despite its high-fat nature, well-formulated ketogenic diets have been associated with improvements in several cardiovascular risk factors. These include reductions in triglycerides, increases in HDL cholesterol, and improvements in the size and quality of LDL particles.
  6. Mental health: Some research suggests that the ketogenic diet may have mood-stabilising effects and could potentially benefit conditions like bipolar disorder and schizophrenia. The mechanisms are not fully understood but may involve the diet’s effects on neurotransmitters and brain energy metabolism.

Considerations & Precautions

While the therapeutic potential of the ketogenic diet is exciting, it’s crucial to approach this dietary change with caution and under professional guidance. The diet may not be suitable for everyone, particularly:

  • Pregnant or breastfeeding women
  • People with kidney disease or pancreatitis
  • Individuals with certain genetic disorders affecting fat metabolism

The ketogenic diet offers a unique approach to wellness that goes beyond simple weight loss. By fundamentally altering our body’s fuel source, it has the potential to address a wide range of health conditions. At Natural Ketosis, we believe in the power of nutritional ketosis to transform health.

As research in this field continues to evolve, we’re likely to gain even more insights into the therapeutic applications of the ketogenic diet. By understanding its mechanisms and potential benefits, we can harness the power of nutrition to support overall health and well-being in ways we’re only beginning to fully appreciate.


Main – Photo by Total Shape on Unsplash

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Hannah is the Founder of three specialist food companies that create food for the Ketogenic Diet based on whole foods. Before setting up the Natural Ketosis Group Hannah was a partner in a large global law firm specialising in corporate and corporate finance law. Her journey from law to nutrition began when she read an article in the British Medical Journal in 2000 reviewing three studies using the keto diet to reverse type 2 diabetes. The article outlined the basic biochemistry of the impact of elevated levels of insulin in the human body. From reading this article, Hannah decided to switch to a Keto/low carb diet and was amazed at how well she felt once she had stripped out the starch and sugar in her diet. The interest in insulin and diet continued to grow until, in 2003, she decided to leave the legal profession and start a food company to make low carb food but free from the rogue ingredients such as sweeteners and soya. Her first business started in 2004 and it was focused initially on low carb keto food options for the public who were mostly looking for weight loss or the management of type 2 diabetes. In 2013 she was approached by the charity Mathews Friends and in particular the founder Emma Wiliams OBE to create a range of food for children with drug resistant epilepsy. This began a deeper dive into the ketogenic diet and with an expert dietician she founded Ketocarefoods that supplies specialist food to the NHS for children with drug resistant epilepsy. Everything made is made from whole food and complies both with requirements of both the classic 3 to 1 ketogenic diet as well as the modified ketogenic diet. In 2020 she created FATT, which is a range of ultra clean and simple snacks for the ketogenic or low carb diet. None of her products have any sweeteners and are free from fillers or other processed ingredients. Hannah has been an advocate of ketogenic whole food diets for over 20 years and is a Patron of the Public Health Collaboration. Her business has been a supporter of charities such as Mathews Friends and Daisy Garland. Hannah is also the author of the book “BIG FAT LIES is our government making us fat?” Her passion is to help health professionals move away from a dependance on drugs for many modern chronic conditions and a greater engagement by the medical and health profession in the use of specific clinically proven diets to reverse and or manage multiple conditions. Hannah was born in London and has a BA in English and History of Art as well as a Diploma in Law. Contact Details Website Facebook Instagram